Most people are surprised to learn that Capsicum (the genus that includes the chillies: small and colorado, very spicy pepper) and, in particular, its active ingredient, capsaicin, are involved in more scientific research than any other genre separately. Only in the last two years have been made over 650 studies on capsaicin, which includes 114 clinical studies in humans. Most of these studies take advantage of the unique mechanism by which the capsaicin produces pain, either to investigate the mechanisms of pain or to relieve chronic pain. Nothing is more fascinating than the use of topical applications of capsaicin cream to relieve the pain of arthritis. Dr. John Mcdougall will undoubtedly add to your understanding. Chronic pain requires the arthritic to use anti-inflammatory and analgesic, medications with serious side effects.
The majority of these drugs are toxic to the liver, kidneys, or both. But chilli cream has no appreciable toxicity. Irritation and heat we experience to the eating chilies is due to that you stimulate certain nerve cells to release a chemical called substance P (substance algogena Pani Substance), responsible for the transmission of painful signals within our nervous system. Capsaicin triggers the release of this neurotransmitter and inhibits the production of more of the same in the body. With the prolonged use of capsaicin is spent, in part, substance P from nerve cells and thus relieves chronic pain (a State that requires substance P).
(Deal et al) researchers at Case Western Reserve University, in Cleveland, assessed the effects of capsaicin, both in patients with osteoarthritis rheumatoid arthritis. They discovered a significant pain relief when applied topically cream with capsaicin in painful knees, four times a day. In rheumatoid arthritis, treatment reduced pain by about half, whereas in osteoarthritis decreased to around a third. The authors conclude that the capsaicin cream is a safe and effective treatment for arthritis. Capsaicin produces additional benefits in patients with rheumatoid arthritis, according to a study by Matucci Cerinic et al., at the Institute of medicine clinic of Italy.